Plenary Lecture
In Silico Approaches in Drug Design
Associate Professor Asad U. Khan
Interdisciplinary Biotechnology Unit
Aligarh M University, Aligarh-202002
India
Email: asad.k@rediffmail.com
Abstract: The aim of this
study was to give a hypothesis for
designing a drug against most
infectious diseases of human
being. There are seven steps in
the drug discovery process:
disease selection, target
hypothesis, lead compound
identification (screening), lead
optimization, pre-clinical trail,
and clinical trial and
pharmacogenomic optimization.
Traditionally, these steps are
carried out sequentially, and if
one of the steps is slow, it slows
down the entire process. These
slow steps are bottlenecks and
could drastically affect the final
outcome of any effort aimed at the
drug development. Drug designing
is a very time taken and costly
process. It is a multistep process
where a single mistake in any step
could result in loss of huge
amount of money and time.
According to estimate, the average
time and cost for a drug is 12
years and $270 million from
initial discovery to public usage
in USA. In silico drug design make
the way more easy and time and
money saving.
Brief Biography of the Speaker:
Asad U Khan, male, molecular
biologist, graduated from
Biochemistry Department, A M
University, Aligarh, India in
1998. He joined Interdisciplinary
Biotechnology Unit, A.M University
as Asst Professor in 1997 and
continued till 2000. He later
joined Department of Biochemistry,
UMDNJ, New Jersey USA in 2000 for
three years as post doctoral
Research Associate, working on
Transcription biology of Yeast and
gene expression. He than resumed
his services as Asst Professor in
the same department till 2006 and
became Associate professor in the
Interdisciplinary Biotechnology
Unit, AMU, India. He was awarded a
prestigious fellowship , BOYSCAST
Fellowship from Government of
India to work as visiting
Scientist in University of Napoli,
Italy in 2005. He was also awarded
Young Scientist Award of
Association of Microbiologist of
India in 2006. His work was well
recognized and he has been invited
several invited talks as well as
reviews articles and chapters. He
has been in Editorial board of
several number of International
journals. He has a total of 55
research articles in his credit.
He is member of several
international associations.
|