Plenary Lecture

Plenary Lecture

In Silico Approaches in Drug Design



Associate Professor Asad U. Khan
Interdisciplinary Biotechnology Unit
Aligarh M University, Aligarh-202002
India
Email: asad.k@rediffmail.com


Abstract: The aim of this study was to give a hypothesis for designing a drug against most infectious diseases of human being. There are seven steps in the drug discovery process: disease selection, target hypothesis, lead compound identification (screening), lead optimization, pre-clinical trail, and clinical trial and pharmacogenomic optimization. Traditionally, these steps are carried out sequentially, and if one of the steps is slow, it slows down the entire process. These slow steps are bottlenecks and could drastically affect the final outcome of any effort aimed at the drug development. Drug designing is a very time taken and costly process. It is a multistep process where a single mistake in any step could result in loss of huge amount of money and time. According to estimate, the average time and cost for a drug is 12 years and $270 million from initial discovery to public usage in USA. In silico drug design make the way more easy and time and money saving.

Brief Biography of the Speaker:
Asad U Khan, male, molecular biologist, graduated from Biochemistry Department, A M University, Aligarh, India in 1998. He joined Interdisciplinary Biotechnology Unit, A.M University as Asst Professor in 1997 and continued till 2000. He later joined Department of Biochemistry, UMDNJ, New Jersey USA in 2000 for three years as post doctoral Research Associate, working on Transcription biology of Yeast and gene expression. He than resumed his services as Asst Professor in the same department till 2006 and became Associate professor in the Interdisciplinary Biotechnology Unit, AMU, India. He was awarded a prestigious fellowship , BOYSCAST Fellowship from Government of India to work as visiting Scientist in University of Napoli, Italy in 2005. He was also awarded Young Scientist Award of Association of Microbiologist of India in 2006. His work was well recognized and he has been invited several invited talks as well as reviews articles and chapters. He has been in Editorial board of several number of International journals. He has a total of 55 research articles in his credit. He is member of several international associations.

 

 

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