Abstract: Historically, mathematics, probability and statistics have been widely used in biological sciences. Science has a challenge to understand a system organization of molecular genetic ensemble with its unique properties of reliability and productivity. Disclosing of key secrets of this organization means a big step in science about nature in a whole and a big step to create the most productive biotechnologies. Knowledge about this structural organization should become a part of mathematical natural science.
Recent advances of mathematical methods and techniques in bioinformatics have been rapidly growing. There is more to life than the genomic blueprint of each organism. Life functions within the natural laws that we know and the ones we do not know. Mathematics can be used to understand life from the molecular to the biosphere level. This talk is devoted to the connection and integration between fundamental mathematical methods and biological sequences, structures, and networks.
The outline of this talk includes:
1. Bioinformatics and Mathematics
2. Genetic Codes, Matrices, and Symmetrical Techniques
3. Biological Sequences, Sequence Alignment, and Statistics
4. Structures of DNA and Knot Theory
5. Protein Structures, Geometry, and Topology
6. Biological Networks and Graph Theory

Brief Biography of the Speaker:
Matthew He, Ph.D., is Full Professor and Director of the Division of Math, Science, and Technology of Nova Southeastern University, Florida, USA. He is Full Professor and Grand Ph.D. from the World Information Distributed University in 2004. He has been awarded as an academician of European Academy of Informatization since 2004. He received the World Academy of Sciences Achievement Award in recognition of his research contributions in the field of computing in 2003.
Matthew He received his Ph. D. in Mathematics from University of South Florida in 1991. He was a research associate at the Department of Mathematics and Theoretical Physics, Cambridge University, Cambridge, England in 1986 and at the Department of Mathematics, Eldgenossische Technische Hochschule, Zurich, Switzerland in 1987. He was also a visiting professor at National Key Research Lab of Computational Mathematics of Chinese Science of Academy and University of Rome, Italy in 1998.
Dr. Matthew He has authored/edited 8 books and published over 100 research papers in the areas of mathematics, bioinformatics, computer vision, information theory, mathematics and engineering techniques in medical and biological sciences. He is an editor of International Journal of Software Science and Computational Intelligence, International Journal of Cognitive Informatics and Natural Intelligence, International Journal of Biological Systems, and International Journal of Integrative Biology. He is an invited series editor of Biomedical and Life Sciences of Henry Stewart Talk “Using Bioinformatics in Exploration in Genetic Diversity”. He is a Chairman of International Society of Symmetry in Bioinformatics and a member of International Advisory Board of "International Symmetry Association (ISA). He is a member of American Mathematical Society (AMS), Association of Computing Machinery (ACM), IEEE Computer Society, World Association of Science Engineering (WASE), and International Advisory Board member of Bioinformatics Group of International Federation for Information Processing (IFIP). He was an international scientific committee co-chair of International Conference of Bioinformatics and its Applications (ICBA 2004), a general co-chair of International Conference of Bioinformatics Research and Applications (ISBRA 2009), and a keynote speaker of many international conferences in the areas of mathematics, bioinformatics, and information science and engineering.