Plenary Lecture
Elaboration and Physicochemical Behaviour of Nano
Hydroxyapatite / Silver Nanoparticles Biocompsite after
"In Vitro" Assays
Professor Hassane Oudadesse
University of Rennes 1, UMR CNRS 6226
263, Avenue du General Leclerc
35 042 Rennes Cedex, France
E-mail:
hassane.oudadesse@univ-rennes1.fr
Abstract: Silver
nanoparticles induce many
beneficiate effects in biomedical
materials when it is used in good
dose. Silver is generally
recognized by its inhibitory
effect towards many bacterial
strains and microorganisms
commonly present in medical and
industrial processes. In this
work,
hydroxyapatite/polyvinylpyrrolidone
was doped with two different
concentrations of silver
nanoparticles prepared by
reduction method.
Physicochemical characterization
of compounds was carried out by
using TEM, SEM and XRD methods.
They permit to highlight the
structural and morphological
behavior of nano biomaterials
after addition of Silver. The
chemical reactivity and kinetic of
bioactivity were studied. Ionic
exchanges between compounds and
SBF were achieved by using ICP-OES
method. It is demonstrated that
silver doped nanohydroxyapatite
obviously improve the bioactivity
of the apatite at the early stages
of immersion. Hydroxyapatite was
elaborated in the presence of
plyvinylpyrrolidone (HA/PVP).
Obtained results show that the
particles seemed to be like fibers
with at least more than 100 nm in
length and 10-20 nm in diameter.
Brief Biography of the Speaker:
Hassane Oudadesse graduated from
the University Blaise Pascal of
Clermont-Ferrand France. He
obtained his PhD in 1989 and
worked as associate Professor and
obtained his HDR (Habilitation a
Diriger des recherches) in 1998.
Since 2001, he works in the
University of Rennes 1 as Full
Professor in the "Sciences
Chimiques de Rennes", UMR CNRS
6226.
His works concern the conception,
synthesis and physicochemical
studies of new biomaterials for
applications in orthopaedic
surgery. Biocompatibility, kinetic
of bioactivity, kinetic of bio
consolidation in the interface
bone-Implants, cells enhancement
and other properties of
biomaterials present the research
filed of Professor Hassane
Oudadesse.
He is author of more than 80
articles published in
international journals and 50
international conferences.
Professor Hassane Oudadesse is a
Head of the research unit on
Biomaterials since 2001,
Vice-President of University of
Rennes 1, human resources since
2008, Director of Master 2 Solid
State Chemistry and Materials
since 2006. He was the President
of the Chemical Department from
2002 to 2004 and the President of
the specialists commission CNU 33
(Materials Chemistry) from 2003 to
2008.
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